Research Grant:

• Department of Microbiology- Virus Research and Diagnostic Laboratory (VRDL) funded by Indian Council of Medical Research (ICMR)/ Department of Health Research (DHR), New Delhi- Funded by ICMR/DHR
• To enhance the quality of infectious disease diagnosis in India through implementation of an External Quality Assurance Program– under National Health Research Priority (NHRP) on One Health- Funded by ICMR/DHR

TRAINING PROGRAMS CONDUCTED

S. No	Subject	Year	No. of personnel trained
1	Sensitization program on VRDL at GTMC	2015	20
2	Availability of VRDL at Govt. Theni Medical College	2016	30
3	Human Resource Development - Workshop on Viral Diagnostics to Post Graduates in Life Sciences	2016	12
4	Human Resource Development - Workshop on Viral Diagnostics to Post Graduates in Life Sciences	2017	11
5	Human Resource Development - Workshop on Viral Diagnostics to Post Graduates in Life Sciences	2018	14
6	Human Resource Development - Workshop on Viral Diagnostics to Post Graduates in Life Sciences	2019	12
7	Human Resource Development - Workshop on Viral Diagnostics to Post Graduates in Life Sciences	2020	15
8	Human Resource Development - Workshop on Viral Diagnostics to Post Graduates in Life Sciences	2021	13
9	Human Resource Development - Workshop on Viral Diagnostics to Post Graduates in Life Sciences	2022	16
10	Human Resource Development - Workshop on Viral Diagnostics to Post Graduates in Life Sciences	2023	20
11	Human Resource Development - Workshop on Viral Diagnostics to Post Graduates in Life Sciences	2024	24
12	Human Resource Development - Workshop on Viral Diagnostics to Post Graduates in Life Sciences	2025	27

Completed research works
 

1. Study on the prevalence of severe acute respiratory syndrome Coronavirus-2 in Theni District, Tamil Nadu.

2. Retrospective Seroprevalence Study of Dengue, Chikungunya and Co-Infection virus: A Hospital Based Study from Theni, Tamil Nadu.

3. Seroprevalence of various viral diseases: A hospital based study.

4. Determination of ‘missed out Dengue NS1’ proportion in Dengue IgM negative population.

5. Serotyping and genotyping of dengue virus circulating in Theni District.

6. Prevalence of HSV, EBV, VZV, CMV, HBV and HCV co-infection among HIV positive individuals.

7. Prevalence of Measles, Mumps, Rubella IgG antibodies among children less than 5 yrs.

8. Prevalence of HSV, EBV, VZV, CMV IgG antibodies among voluntary blood donors.

9. Determination of proportion of Dengue positivity in voluntary blood donors: A pilot study.

10. Studies on Genomic Epidemiology of SARS-Cov2 from Theni, Tamilnadu.

11. Seroprevalence and clinical profile of Leptospirosis and Scrub typhus in clinically suspected patients in a tertiary care center: A Retrospective study from Theni, Tamil Nadu.

12. Seroprevalence, Quantification and risk factors for Hepatitis B and Hepatitis C Viral Load by Real-Time PCR in clinically suspected patients attending a tertiary care hospital.

13. Evaluation of Dried Blood Spots (DBS) for Scrub Typhus Diagnosis using ELISA

 

Ongoing research works

1. Development of genotyping-based RT-qPCR platform for Hepatitis A Virus Assay using Serum and Stool Specimens

2. Clinical and serological differentiation of primary and secondary dengue infections - A cross sectional study in a tertiary care centre.

3. Molecular analysis of influenza virus circulating in Theni district.

4. Genotyping of Hepatitis A and E viruses circulating in Theni District.

5. Anti Dengue virus properties of small molecule natural compounds.

6. Factors influencing the transmission, diagnosis, management and treatment outcome of viral hepatitis with special emphasis on high-risk population

7. A prospective study on changes in gut microbiome signatures with the progression of Hepatitis B Virus & C Virus infection before and after treatment.

8. Mapping dengue virus (DENV) serotype-specific neutralizing epitopes on envelope E protein by deep mutational scanning.

9. Studies on viral load and immune correlates in HIV & HBV and HIV & HCV co-infection.

10. Clinical and serological differentiation of primary and secondary dengue infections - A cross sectional study in a tertiary care center.

Research publications

1. Ramlingam, Gopinath; Muthukumar, Arundadhi; Aridass, Dhanasezhian; Ganesan, Sucila Thangam. Seroprevalence and Clinical Profile of Leptospirosis and Scrub Typhus in Clinically Suspected Patients at a Tertiary Care Center: A Retrospective Study from Theni, Tamil Nadu. Biomedical and Biotechnology Research Journal 8(3):p 382-386, Jul–Sep 2024. | DOI: 10.4103/bbrj.bbrj_192_24

2. Sucila Thangam G, M. Arundadhi, M. Amudhan, R. Gopinath. Antimicrobial Potentiality of a New Beta Lactam Antibiotic Fosfomycin among Multidrug Resistant, Extended Spectrum Beta Lactamase Producing, Carbapenem Resistant Uropathogens. International Journal of Pharmaceutical and Clinical Research 2024; 16(7); 360-366. e-ISSN: 0975-1556, p-ISSN:2820-2643

3. Gopinath R, Arundadhi M, Thangam GS. Recognizing The Significance of Scrub Typhus as An Emerging Threat. Natl J Community Med 2024;15(7):615-616. DOI: 10.55489/njcm.150720243946

4. Gopinath Ramalingam, Muthukumar A, Sivadoss R, Rajan G, Aridass D, Murugesan A, et al. Genomic epidemiology of severe acute respiratory syndrome coronavirus 2 from Theni, Tamil Nadu. J Family Med Prim Care. 2024;13:1727-33. https://doi.org/10.4103/jfmpc.jfmpc_1698_23

5. Gopinath R.; Arundadhi M.; Dhanasezhian A.; Thangam G. Sucila. From gut to brain: Deciphering the impact of gut microbiota on neurological health. Novel Research in Microbiology Journal (2024), 8(2): 2339-2353. DOI: 10.21608/NRMJ.2024.273319.1479

6. Gopinath Ramalingam, Arundadhi M, Revathi R, Sowndarya M, Dhanasezhian A, Thangam GS. Exploring the Potential of Human Papilloma Virus: An Overview. Natl J Community Med 2023; 14(12):866-875. DOI: 10.55489/njcm.141220233369

7. Gopinath R, Sundaram AL, Dhanasezhian A, Arundadhi M, Thangam GS. Seroprevalence of various viral diseases: A hospital‑based study. Journal of Global Infectious Diseases.2023; 15:144-8.  I.F-1.6

8. Gopinath R, Gopinathan R, Jegatheesh R, Dhanasezhiyan A, Amudhan M, Lallitha S. Study on the prevalence of severe acute respiratory syndrome Coronavirus-2 in Theni District, Tamil Nadu. Biomedical and Biotechnology Research Journal (BBRJ). 2023 Apr 1;7(2):176-80. I.F-1.4

9. Gopinath R, Dhanasezhiyan A, Krishnapriya S, Prasanth SM, Thangam GS. A Retrospective Seroprevalence Study of Dengue, Chikungunya and Co-Infection virus: A Hospital Based Study from Theni, Tamil Nadu. Journal of Pure & Applied Microbiology. 2023 Sep 1;17(3). I.F-0.8

10. Gopinath R, Arundadhi M, Vijay S, Dhanasezhian A, Thangam GS. A Review on the Seasonal and Pandemic Potential of Influenza a (H3N2) virus. Tuijin Jishu/Journal of Propulsion Technology. 2023 Sep 11;44(3):1339-46.

11. Poornakala Ramu, M. Udayashri, M. Basheer Ahamed, Nithyagomatheswari Subbiah, T. Jeyamurugan, V. Kalaivani, R. Gopinath, T. Sankaranarayanan. Evaluation of antimicrobial resistance and characterization of virulence factors of Pseudomonas aeruginosa isolates with special reference to biofilm formation. Biomed Biotechnol Res J 2023; 7:450-7. I.F-1.4

12. Aridass Dhanasezhian, Murugesan Amudhan, Sucila Thangam. Low Prevalence of Mumps IgG Antibodiesamong the Paediatric PopulationAttending Tertiary Care Hospital in Southern India- A Pilot Study. Jan 2023 Journal of Clinical and Diagnostic Research.

13. Ganesan M, Sudha R, Amudhan M, Thangam GS. Lesson learned: Retrospective analysis of ‘missed out’ dengue NS1 positives among IgM negative population. Asian Pac J Trop Med.2020 [cited 2020 Oct 20];13:221-6 

14. Anbalagan A. Meena, Amudhan Murugesan, Surliappan Sopnajothi, Yean K. Yong, P. Sankar Ganesh, Irudhayaraj J. Vimali, Ramachandran Vignesh, Manickan Elanchezhiyan, Meganathan Kannan, Aditya P. Dash, and Esaki M. Shankar. Increase of Plasma TNF-α Is Associated with Decreased Levels of Blood Platelets in Clinical Dengue Infection.Viral Immunology.Feb 2020.54-60.

15. Sathappan U. Preeyaa, Amudhan Murugesan, Surliappan Sopnajothi, Yean K. Yong, Hong Y. Tan, Marie Larsson, Vijayakumar Velu, and Esaki M. Shankar. Peripheral Follicular T Helper Cells and Mucosal-Associated Invariant T Cells Represent Activated Phenotypes During the Febrile Phase of Acute Dengue Virus Infection. Viral Immunology.ahead of print http://doi.org/10.1089/vim.2020.0149 

16. Murugesan A, Aridoss D, Senthilkumar S, Sivathanu L, Sekar R, Shankar EM, et al. Molecular diversity of dengue virus serotypes 1–4 during an outbreak of acute dengue virus infection in Theni, India. Indian J Med Microbiol 2020;38.

17. Rao C, Kaur H, Gupta N, Sabeena SP, Ambica R, Jain A, Yadav A, Dwibedi B, Malhotra B, Kakru DK, Biswas D, Ganesan, M.; Sabat, Jyotsnamayee; Dhingra, Kanwardeep; Lalitha, S. Geographical distribution of primary & secondary dengue cases in India–2017: A cross-sectional multicentric study. The Indian journal of medical research. 2019 Apr;149(4):548.

18. Swarna. S, Lallitha. S, Amuthan. M, Ganesan . M, Rajkumar. M, Dhanasezhian. A , Sekhar. R, K. M. Mythreyee, Study on prevalence of dengue fever in a tertiary care hospital, south India, Global journal for research analysis, VOLUME-7, ISSUE-1, JANUARY-2018.

19. Ganesan M, Thangam GS, Sekar R, Sudha R. Laboratory Request Form Revamped: Pictogram Based Symptoms Afford Adequate Patient's Clinical Information in High Patient Load Setting. Journal of Clinical & Diagnostic Research. 2019 Sep 1;13(9).

20. Ganesan Mahadevan, Sucila thangam Ganesan,Ramalingam sekar, Robert Sudha. Laboratory Request Form Revamped: Pictogram Based Symptoms Afford Adequate Patient's Clinical Information in High Patient Load Setting. September 2019. Journal of Clinical and Diagnostic Research 13(9):LC19-LC22.

 

Book Chapter:

Title: Evolution of the Ebola virus into deadliest viruses of mankind

Author: Gopinath Ramalingam, Gowsalya Saminathan, Gopinathan R, Krishnapriya S and Lallitha S

Book: Recent Advances in Microbiology Research

Edition: Volume -1 Edition-1-2021

First Published: 2021 

Imprint: Darshan Publishers,

Pages : 1-9

eBook ISBN : 978-81-954602-3-6

 

Title: Impacts of Delta variant in SARS CoV 2 Evolution

Author: Krishnapriya Subramani, S. Swarna, Lallitha S and Gopinath Ramalingam 

Book: Recent Advances in Microbiology Research

Edition: Volume -1 Edition-1-2021

First Published: 2021 

Imprint: Darshan Publishers,

Pages: 10-22

eBook ISBN: 978-81-954602-3-6

 

Title: Emergence of Viral Hemorrhagic Fever as a Global Threat

Author: R. Gopinath, A.L. Meenakshi Sundaram, A. Dhanasezhian and G. Sucila Thangam

Book: Research in Microbiology

Edition: Volume -8 

First Published: 2023 

Imprint: AkiNik Publications TM,

Pages: 37-55

Book DOI: https://doi.org/10.22271/ed.book.2282

ISBN: 978-93-5570-773-4

 

Title: Assessing the Prevalence and Seroprevalence of Acute Dengue and Chikungunya Virus Infections from Theni, Tamil Nadu, India: A Retrospective Hospital-Based Study

Author: R. Gopinath , M. Arundadhi , A. Dhanasezhian a, M. Sowndarya, Daya Pauline S. and G. Sucila Thangam

Book: Medical Research and Its Applications 

Edition: Volume -1

First Published: 2024 

Imprint: BP International

Pages: 109-121

Book DOI: https://doi.org/10.9734/bpi/mria/v1/307

Print ISBN: 978-81-973316-2-6

eBook ISBN: 978-81-973316-4-0

Title: Engineered Phage Therapy and Drug Delivery: Mechanisms, Applications, and Challenges

Author: R. Gopinath , M. Arundadhi , A. Dhanasezhian and G. Sucila Thangam

Book: Current Knowledge on Novel Drug Delivery Systems 

Edition: Volume -1

Publication Year: June, 2024 

Imprint: Prime Publication, New Delhi, India

Pages: 01-23

Print ISBN: 979-65-826159-1-6